Side effect of coronavirus: scientists have discovered the most dangerous consequence of COVID-19

Scientists around the world are studying the most dangerous side effect of COVID-19 - the formation of blood clots. Studies in the Netherlands and France indicate that thrombosis occurs in 20-30% of patients with coronavirus. Practitioners call even more alarming figures. This is stated in the video "Voices of America".

“There are a lot of studies. If we try to generalize, a third of seriously ill patients develop blood clots, although some studies suggest that we are talking about 50-70%,” says Rupin Arya, professor of medicine at King’s College Hospital.

Like other complications, blood clots, often fatal, develop due to the overreaction of the immune system to coronavirus. Hematologists practicing doctors say they have not seen anything like it before.

“Usually, blood clots are the body’s response to minor injuries, but the current reaction is simply off scale. Thrombosis is observed in large and small vessels. The extent of the vascular inflammation we are seeing suggests that in addition to the usual blood clots, many patients are developing clots in the smallest blood vessels, especially in the lungs. We have to recognize that it affects a number of organs, including the kidneys and intestines,” says Aria.

Through blood, COVID-19 attacks the entire body. Scientists have called thrombosis one of the key factors that make the disease so dangerous.

“It’s amazing how many manifestations of blood clots we see with COVID-19: clots form in the veins of the legs, in the lungs, what is even more surprising, they form in the vessels of the brain of young patients, causing strokes, as well as in the heart, and in the absence of primary lesions - there are not even ordinary atherosclerotic plaques,” says Robert Flomenhaft, professor of hematology at Harvard Medical School.

Now everyone who enters the hospital with COVID-19 in the USA is trying to give blood thinners, which are usually given to stroke patients.

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“The anticoagulants we currently use increase the risk of bleeding and therefore we need to be careful. On the one hand, it protects against blood clotting, and on the other, it doesn’t cause bleeding,” Flomenhaft said.

Doctors found that often the standard doses of such drugs simply do not work, the blood becomes so thick in patients.

“According to some studies, when using a standard dose of coagulants, almost half of patients develop large blood clots and potentially life-threatening blood clots. As a result, some hospitals are increasing doses to try to prevent blood clots in these patients, especially severely affected patients in intensive care,” Ariya said.

A number of patients have a sharp increase in blood protein levels called D-dimer. Protein is formed during the breakdown of blood clots, its presence is a sign of the likelihood of a fatal outcome.

“If a patient is prone to blood clots, if he already has a blood clot, the levels of this protein in the blood range from 0 to 200. Surprisingly, in the situation with COVID-19, the range is from 50 to 100 thousand, which indicates a huge number of blood clots.” , said hematologist Jeffrey Lawrence.

Studies explain why patients have been on artificial ventilation machines for weeks, because even the oxygen supplied through them hardly penetrates the blood due to blockage of the blood vessels of the lungs.

“During the autopsy, we found blood clots in the blood vessels, but did not find other types of pathologies characteristic of extensive pneumonia. The clinical picture was different: less inflammation, destruction of blood vessels, but a large number of blood clots,” says Lawrence.

Doctors believe that thrombosis explains the sudden death of patients with COVID-19, as well as a sharp deterioration in their condition. Since there is no cure for coronavirus yet, scientists are faced with the task of identifying groups of people most prone to blood clots. For example, it is known that men at the age of 40 are at risk.

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