Scientists have found a molecule that destroys even the most dangerous types of cancer

Scientists working at Yale University and the University of Rhode Island (URI) have discovered a new molecular cancer treatment that can target cancer cells and destroy tumors in mice. So far, the tests have produced exceptionally spectacular results, and even one dose has been enough to destroy some of the most advanced tumors. Writes about it BGR.

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A new cancer treatment is based on a specific molecule that can seek out the acidic environment surrounding cancer cells. But in order for the cells to be sufficiently acidic, they cannot be "cold" tumors with little immune activity.

This is where drugs known as STING agonists come into play. They "trigger" tumors allowing the immune system to respond to them.

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However, finding "cold" cancer cells can be difficult. This is where the new molecular treatment for cancer comes into play. According to the study, the molecule is called a low pH insertion peptide (pHLIP), and it is attracted to acidic environments.

By using the molecule to direct a drug to tumors and cancer cells, scientists bring the tumor out of its "cold" range and force the immune system to fight back against the harmful formation.

Scientists then use immune checkpoint inhibitors to remove the “natural brakes” that prevent the immune system from fighting cancer at its full potential. This molecular cancer treatment allows the immune system to fight the disease for a longer period of time.

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It's a dual system that basically allowed researchers to target drugs exactly where they needed them. In recent years, more and more targeted options have emerged, such as this new molecular treatment for cancer. A virus that targets cancer cells is also in development. Researchers are testing a gel that kills skin cancer, among other things.

In testing a molecular cancer treatment, the researchers coupled pHLIP with STING agonists and then treated 20 mice with colorectal tumors. They found that after a single injection in 18 mice, the tumors completely disappeared within a few days. In another group with larger tumors, they observed the disappearance of tumors in seven of 10 treated mice.

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