100 clone of thousands of dollars: how the rich pay a fortune for copies of dead dogs - ForumDaily
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100 clone of thousands of dollars: how the rich pay a fortune for copies of dead dogs

More than 10 years in the Seoul laboratory "create" copies of dead animals for customers who have not found the strength to part with the pet.

Фото: Depositphotos

“1108” - such a number was obtained by a puppy of the Central Asian Shepherd Dog, as soon as the specialists of the Seoul laboratory successfully completed the maternity operation. At the same time, another doctor was working on the baby’s mother, who was bred specifically for carrying cloned puppies. “This is a mixed look. We breed surrogate mothers so that they are obedient and gentle, ”says Zhe Ung Wang. He works for the Biotech Research Foundation, a leading dog cloning company.

More than 20 years have passed since the first successful cloning of a mammal, Dolly the sheep. And from the first part of the film “Jurassic Park” about the successful cloning of dinosaurs - even more. The interest of people and the media has long switched from the topic of cloning to other scientific discoveries, but all this time South Korean scientists continued large-scale experiments. And this made them both great allies and opponents. Details of the dog cloning business were told by Vanity Fair, the translation of which is given by TJournal.

Clone for 100 thousand dollars

In March, 2018, the singer Barbra Streisand, first admitted that her two Coton de Tulear puppies are clones of her dog, who died in the 2017 year. For 50 thousands of dollars a Texan company took DNA samples of a dead animal and based on this data cloned puppies.

“I was so devastated by the loss of my dear Samantha. It was easier for me to let her go, knowing that I would save at least some part of it, ”explained the singer.

Activists and animal defenders negatively received the recognition of Streisand, comparing what happened with the plot of the anti-utopian series about the near future “The Handmaid's Tale”. The resonance once again caused a broad discussion of the topic of cloning, which was repeatedly raised both within the walls of the White House and in the Vatican. One of the main questions was: “Does humanity have the right to recreate a copy of a living being, given the pain and anguish that it goes through during childbirth?”.

To create one healthy puppy, up to a dozen embryos are taken away that the mother carries. Sometimes animals are injected with hormones, which in incorrect doses can lead to miscarriage, as well as to the appearance of a puppy with physical disabilities or dead. For the first successful dog cloning experience in 2005, it took more than a hundred queens and about a thousand embryos. “This is the canine version of reproductive machines,” says ethic and dog expert Jessica Pierce, referring to surrogate mothers.

However, in the Seoul laboratory, according to the correspondent of Vanity Fair, everyone is smiling. Including the representative of the client who paid for the number "1108". First, this thin man of Middle Eastern appearance spoke to someone from the staff, and then took some photos with a newborn puppy.

Over the past ten years, the Biotech Research Foundation has cloned more 1000 dogs, the price for the "creation" of which is 100 thousands of dollars.

Dog cloning is a business. If the owner of the dead dog provides her DNA samples within five days of death, the company will replace it in about five months.

The man who "created" the dog

In 2004, the veterinarian and researcher Hwang Wu Sok, while working at the laboratory at Seoul University, announced that he and his team had successfully cloned a human embryo. A year later, he created a copy of a puppy, using DNA cells from the ear of the Afghan hound. Hwan has planted fetuses in the uterus for 123 surrogate mothers, but only one has given birth to a healthy puppy.

However, the fame was short-lived — in 2006, the scientist was fired from the laboratory for fraud — in fact, he did not succeed in cloning the human embryo. He took advantage of this fiction to get government funding and complete his project to create a copy of a dog. Initially, the veterinarian was sentenced to two years in prison, but later the punishment was canceled. As the judge explained, Khvan “demonstrated convincing evidence of remorse.”

Having escaped prison, the South Korean continued his research. He concentrated on cloning pigs and cows, but in 2007, a representative of billionaire and founder of the University of Phoenix, John Sperling, unexpectedly contacted him. The businessman explained that several years ago a dog had died with his lover. The woman dreamed of returning the animal, and Sperling turned to Hwan. Two years later, he safely fulfilled the order, receiving additional money to expand the business.

The process itself, carefully regulated through years of trial and error, is known as "the transplantation of somatic cell nuclei." It all starts with an egg from a donor dog: using a high-powered microscope, scientists pierce a microcell in the egg and remove the nucleus where DNA is located.

Then they replace the nucleus with a cage from a dog that needs to be cloned - usually a piece of skin or the inside of the cheeks serves as the core. Then a small charge of current is passed through the hybrid egg to cause cell division, after which the embryo is inserted into the surrogate uterus. If the transfer is successful, a puppy will be born in 60 days.

When asked why so many people want to clone their dogs, Hwang answers simply: the dog is a family member, and the owners want to continue to communicate with him for as long as possible. The scientist emphasizes that customers do not receive an exact copy of the deceased pet. Often clones look identical to the original and even repeat some of their features, but they have no real dog memories.

Hwan prefers not to go into the ethical side of cloning. He points out that making copies of animals is fundamentally different from human cloning (the company opposes this) and can be beneficial to society. There is a common sense in this: through the study of animal embryos in the laboratory, they are looking for ways to combat Alzheimer's disease and diabetes.

In addition, Hwan is exploring the possibility of "reviving" a woolly mammoth with the help of the skin of extinct creatures, which was found in Siberian ice. The scientist's plan is to cross the DNA of a mammoth with the egg of a modern elephant. If successful, this will be the first hybrid of an elephant and a mammoth.

Closed story

Despite the success of Hwan, his reputation has not yet recovered after the disclosure of deception. The South Korean government continues to prohibit the researcher from conducting any experiments on human eggs and stem cells. However, this does not prevent the business of a scientist from growing: Streisand approached him on the advice of the American businessman and co-founder of the FOX television channel Barry Diller.

Shortly before that, he appealed to the South Korean scientist with a request to “return” to him a dead pet Jack-Russel Terrier. As a result, the businessman received three clones of the dead animal that were almost identical in appearance. Two of them live in the Diller mansion in Beverly Hills, and the third is with his wife and model Diana von Furstenberg in Connecticut.

However, not all belong to the cloning of pets so loyal. After the death of his beloved dog, the British journalist and magazine publisher Tom Rabiton could not decide on the procedure for a long time. He was embarrassed by the unnaturalness of the venture, but even more frustrated by the prospect of never seeing his dog again. To pay for the operation required 100 thousand dollars, the reporter sold two cars of the brand Mercedes SL. The operation was successful, and Rabiton received two puppies.

They are very similar, but still different. One looks almost like the original, and the other is more like a sister [of a dead dog]. This is 85%, not 100%. They are looking at me right now. They know what I'm talking about.

Tom Rabiton
journalist

Researchers at the Biotech Research Foundation insist that their cloning procedures are ethical, and they plan to achieve even more in the future. At the moment, the biggest problem of cloning dogs is that they need to extract eggs from live animals. So far there is no technology that would allow dogs to grow eggs separately. According to the laboratory, over the years 13, the practice of implanting additional hormones into carriers has almost disappeared. Often, current technologies can do without this ambiguous procedure, according to company employees.

“Cloning is ineffective. In the process, you lose a lot of clones. Some die during implantation, ”says Rudolf Jaenisch, a leading expert on stem cell research at the Whitehead Institute in Cambridge. According to him, the Biotech Research Foundation conceals the truth about the real difficulties with cloning. He also added that the lifespan of copies of dogs is noticeably below the standards, but so far it is difficult to verify in practice due to the relatively small age of the puppies.

Following the story of Streisand, animal rights activists tweeted a campaign “take in the family, not clone”, the essence of which is to call for dogs from a shelter, and not to go to the cloning laboratories. “It seems that people who spend 100 thousands of dollars to create a new dog do not remember at all those many animals that nobody cares about,” said Vicki Katrinak, head of the regional research center in the United States.

Future cloning

In January, 2018, for the first time Chinese scientists cloned monkeys by the method of sheep Dolly. As Hwan says, these primates are extremely similar to humans, which opens up new horizons for development for specialists.

However, the successful cloning of two monkeys required 63 surrogate mothers - it is doubtful that a similar process will be approved for people. “Can you imagine creating a human clone using so many surrogate mothers?” Can you imagine that such a procedure will pass a clinical examination? And if you get a child with physical or mental disabilities? ”- Stanford Bioethics Greely asks questions.

But experts admit that it will not take long before the grieving parents contact the laboratory with a request to “return” the lost child. However, even this is no longer impressive scientists. In their dreams, people will not only be able to clone, but to completely modify the structure of the DNA of clones in order to make them stronger, faster and better. Despite protests by activists and government bans, the world, scientists believe, is closer than ever to human cloning. And only a matter of time when someone wants to take advantage of it.

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