Two doses were not enough: Pfizer suggests giving children under 5 three vaccinations against COVID-19

Early analysis showed two doses of COVID-19 vaccine were ineffective in some young children, Pfizer said. The company plans to make adjustments to an ongoing study to test the efficacy of a third dose. Writes about it NBC New York.

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“Compared with people aged 16 to 25 years, who were found to be highly effective, noninferiority was found for the 6 to 24 month group, but not for the 2 to 5 year group,” Pfizer said in a statement.

The company will now consider a third dose two months after the second in children ages 6 months to 5 years.

Pfizer said that if the three-dose regime works, it plans to apply for an emergency use authorization to regulators in the first half of next year.

Pfizer's children's version of the vaccine is already available for children ages 5 to 11, accounting for a third of the dose given to everyone else 12 and older. Independent.

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For children under 5, Pfizer is testing an even lower dose, just 3 micrograms, or a tenth of the adult dose.

The researchers analyzed a subgroup of children in the study one month after taking the second dose to see if they developed antibody levels similar to those of adolescents and young adults who received the vaccine.

Toddlers under 2 years of age had similar antibody levels, but the immune response was lower in children 2 to 4 years old, said Pfizer vaccine research leader Katrin Jansen.

No security issues were found in the study, according to a company spokesman.

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Jansen cited data showing that booster shots for people 16 and older restore strong defenses. A spike in immunity is taking place, which scientists hope will help ward off the new omicron strain.

The company, among other things, is preparing to test a booster for children aged 5 to 11, who are currently receiving only two-dose vaccinations. And they are testing different booster doses for teens.

Jansen noted that if additional testing is successful, "we will have a consistent approach to vaccination with three doses for all ages."

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