Doctors in the US Cure Cancer of the End-Stage Breast Cancer

American scientists with the help of a new procedure managed to save a woman from breast cancer, which passed into the terminal stage. As part of a new therapy, 90 billion of immune cells were pumped into the blood of a woman.

Two years ago, doctors told Judy Perkins from Florida that she had three months left to live. Today in her body there is no trace of a cancerous tumor.

A team of scientists from the National University of the USA for cancer research says that the treatment is still experimental, but in the future it can change how the cancer is treated in the world.

Judy had terminal breast cancer that was spreading rapidly—too late for standard treatment.

Judy's liver had a tumor the size of a tennis ball, and metastases all over her body.

“A week [after undergoing therapy] I started to feel something. “I could feel the swelling in my breast shrinking,” she says. “After another week or two it disappeared completely.”

Judy remembers the first time she was shown a CT scan after the procedure: all the medical staff were “almost jumping for joy,” she says.

Then she was first told that she would most likely be cured.

Today, Judy spends his days hiking and riding a sea kayak. She recently completed a five-week trip to Florida.

Live medicine

The new technology is called "living medicine." The drug is made from the patient's own cells in one of the world's leading cancer research centers.

“We're talking about the most personalized treatment imaginable,” says the university's chief of surgery, Dr. Steven Rosenberg.

The technology is still experimental, and before you begin to apply it more widely, extensive testing is needed, but here's how it works: first you need to study the enemy.

Each patient's tumor is examined at the genetic level to identify those mutations that can make the cancer “visible” to the human immune system.

In Judy’s case, 62 genetic abnormalities were identified in her tumor, four of which scientists were able to use to attack the tumor.

The next stage is hunting. The patient's immune system already attacks the cancer, but loses. Therefore, doctors analyze the white blood cells in the patient’s blood and identify those that can fight cancer.

Then, similar white cells are created in large quantities in the laboratory.

About 49 billions of such cells were injected into 90-year-old Judy.

“The mutations that were the cause of cancer turn out to be its Achilles heel,” says Dr. Rosenberg.

"Paradigm Shift"

These are the results of the treatment of one patient, and further extensive studies are needed to validate the method.

The problem of using immunotherapy to fight cancer is that it works wonders for some patients and does not work for most.

“The procedure is experimental, we are still learning how to do it correctly, but potentially in the future it could be applied to any cancer,” says Dr. Rosenberg.

“There is a lot of work to be done, but there is potential for a paradigm shift in cancer treatment towards developing a unique drug for each patient - this is very different from other types of treatment,” he adds.

Fully study can be found in Nature magazine..

Dr. Simon Vincent, Head of Motion Research Breast Cancer Now, believes that the research of American scientists “meets world standards.”

“We think this is an outstanding result,” the scientist said in an interview with Bi-bi-si. “This is the first opportunity to see how such immunotherapy works against the most common type of cancer. It was only tested on one patient,” says Vincent.

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