Scientists first created an antibody that neutralizes coronavirus in human cells

Although there is currently no known cure for COVID-19 disease, the researchers first created an antibody that "neutralizes SARS-CoV-2" in human cells, offering potential for the prevention and treatment of coronavirus infection, writes Fox News.

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The study notes that the antibody, known as 47D11, was created in a laboratory environment and is able to inactivate the so-called spike proteins found in SARS-CoV-2, the virus that causes COVID-19, as well as in the SARS-CoV virus that causes acute illness. respiratory syndrome.

“Our data indicate that 47D11 neutralizes SARS-CoV and SARS-CoV-2 through a yet unknown mechanism that is distinct from receptor-binding interference,” the researchers wrote in their paper. “Alternative mechanisms for antibody neutralization of coronavirus have been reported, including inactivation of the spike protein through destabilization of the structure.”

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The SARS-CoV virus, which causes acute respiratory syndrome (SARS), first appeared in China in 2002 and triggered an outbreak in 2002-2004. According to the Centers for Disease Control and Prevention, the virus associated with horseshoe bats has led to 774 known deaths.

Antibody 47D11 is a monoclonal antibody that has previously been used to develop a cancer drug, the Mayo Clinic reports.

Monoclonal antibodies are defined as “laboratory-produced molecules designed to be used as replacement antibodies,” added Mayo Clinic.

Researchers noted that the process of developing a potential drug is at an early stage, but, nevertheless, the result is promising.

“This antibody will be useful for the development of antigen detection tests and serological assays targeting SARS-CoV-2. Neutralizing antibodies can modify the course of infection in an infected person by supporting the body to clear the virus, or protect an uninfected person who is exposed to the virus. Therefore, this antibody—alone or in combination—has the potential to prevent and/or treat COVID-19, as well as possibly other future diseases in humans caused by viruses.”

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The study was published in a scientific journal. Nature Communications..

As of the morning of May 5, over 3,6 million cases of coronavirus have been diagnosed worldwide, more than 1,18 million of which are in the United States, the most affected country on the planet.

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