You can eat junk food and not spoil your health: scientists told how
French scientists from the University of Franche-Comte proved that polyphenol-containing plant extract cancels the negative effects of eating large amounts of fats and carbohydrates and increases the average life expectancy in mice with excess weight.
According to the authors of the work, published in the journal Scientific Reports, the mixture will also prevent violations in the metabolism and ensure a long and healthy life in people with obesity, writes Lenta.ru report.
First, researchers assessed the effect of different diets on obesity and pathogenic processes in mice. Some of the animals received food with a high amount of fat or sucrose, the rest of the rodents fed on standard food. At the same time, the former developed hyperglycemia (elevated blood sugar), increased cholesterol levels, increased oxidative stress, increased the mass of adipose tissue and significantly decreased the average lifespan (from 596 to 381 of the day).
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At the same time, one of the factors causing diseases associated with obesity was the penetration of immune cells into the adipose tissue, provoking inflammation. This also contributed to dysbiosis and damage to the intestinal mucosa (intestinal barrier), which absorbs nutrients and prevents the penetration of harmful substances into the bloodstream.
In another part of the experiment, mice sitting on an unhealthy diet were given a plant extract enriched with polyphenols. It contributed to a much slower increase in body weight and an increase in life expectancy from 381 to 681 of the day. Plasma cholesterol level, indicators of oxidative stress and the content of bacterial toxic substances in the intestine decreased. In addition, the immune reactions associated with inflammation also returned to normal.
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Although obesity has long been viewed as associated with a high mortality rate due to metabolic disorders and cardiovascular diseases, in recent years, more and more works have appeared proving the possibility of benign or healthy obesity. Although cardiovascular disorders in overweight people are still greater than those of lean people, the risk of their development is much lower for them than for those who are suffering from obesity and metabolic disorders at the same time.
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