Scientists have discovered several drugs and even dietary supplements that help against COVID-19 - ForumDaily
The article has been automatically translated into English by Google Translate from Russian and has not been edited.
Переклад цього матеріалу українською мовою з російської було автоматично здійснено сервісом Google Translate, без подальшого редагування тексту.
Bu məqalə Google Translate servisi vasitəsi ilə avtomatik olaraq rus dilindən azərbaycan dilinə tərcümə olunmuşdur. Bundan sonra mətn redaktə edilməmişdir.

Scientists have discovered several drugs and even dietary supplements that help with COVID-19

In a new study by the University of Michigan, scientists have learned that several COVID-19 drug contenders are already being used for other purposes. Writes about it "New Time".

Photo: Shutterstock

Among these drugs, there is even one nutritional supplement that has been shown to block or reduce SARS-CoV2 infection in cells.

The scientists used image analysis of human cell lines when infected with COVID-19. The analysis was carried out using artificial intelligence. Cells were treated with more than 1400 drugs and compounds, before or after viral infection. As a result, scientists have selected 17 potential drug options for COVID-19.

Семь из этих соединений были обнаружены в предыдущих исследованиях перепрофилирования лекарств, включая ремдесивир, который является одним из немногих одобренных Администрации по контролю качества пищевых продуктов и медикаментов США (FDA) препаратов для лечения COVID-19 у госпитализированных пациентов. А вот еще 10, и в том числе — одна биодобавка — были отмечены учеными впервые.

«Традиционно процесс разработки лекарств занимает десятилетия, а у нас просто нет десятилетий. Обнаруженные нами методы лечения хорошо подходят для фазы 2 клинических испытаний, поскольку их безопасность уже установлена​​», — сказал Джонатан Секстон, доктор философии, доцент кафедры внутренней медицины Медицинской школы Университета Мичигана и один из ведущих авторов статьи.

On the subject: In the United States, the third vaccination against COVID-19 will be injected: who needs it

The team tested 17 candidate compounds in multiple cell types, including stem cell-derived human lung cells, in an attempt to mimic SARS-CoV2 infection in the airways. Nine of these have shown antiviral activity at reasonable doses, including lactoferrin, a protein found in human breast milk. It is also sold as a dietary supplement derived from cow's milk.

«Мы обнаружили, что лактоферрин обладает превосходной эффективностью в предотвращении инфекций, работая лучше, чем все, что мы наблюдали», — сказал Секстон. Он добавляет, что ранние данные предполагают, что эта эффективность распространяется даже на новые варианты SARS-CoV2, включая вариант Дельта.

The team will soon begin clinical trials of this compound to study its ability to lower viral load and inflammation in patients with SARS-CoV2 infection.

Notably, the study also identified a class of compounds called MEK inhibitors that are commonly prescribed to treat cancer that appear to worsen SARS-CoV2 infection. The find sheds light on how the virus spreads among cells.

«Люди, проходящие химиотерапию, уже подвергаются риску из-за пониженной иммунный ответ. Нам необходимо выяснить, ухудшают некоторые из этих препаратов прогрессирование болезни», — сказал Секстон.

You may be interested in: top New York news, stories of our immigrants and helpful tips about life in the Big Apple - read it all on ForumDaily New York.

Earlier, the Australian-American research team reported "promising results" in their mouse trials of new drugs for COVID-19.

The technology is based on "short interfering RNA", which prevents the replication of the virus inside human cells.

The authors of the work from the Menzies Institute of Health at Griffith University found that the number of viral particles in the studied mice decreased by 99,9%. While the results are promising, the technology has only been tested in mice.

Researchers suggest that the drug can be administered to patients daily for up to five days, for example, sick in a hospital, or at a time if someone has just been exposed to the coronavirus; however, there is no concrete data on this yet.

Read also on ForumDaily:

COVID-19 pandemic + wildfires: virus and smoke double hit US residents

San Francisco residents unvaccinated from COVID-19 will not be allowed in restaurants and gyms

'This is a disaster': five US states set new records for the number of cases of COVID-19

Vaccine or prison: US judges pass unusual sentences

medicine Educational program Special Projects COVID-19
Subscribe to ForumDaily on Google News

Do you want more important and interesting news about life in the USA and immigration to America? — support us donate! Also subscribe to our page Facebook. Select the “Priority in display” option and read us first. Also, don't forget to subscribe to our РєР ° РЅР ° Р »РІ Telegram  and Instagram- there is a lot of interesting things there. And join thousands of readers ForumDaily New York — there you will find a lot of interesting and positive information about life in the metropolis. 



 
1077 requests in 1,184 seconds.