Pfizer announced the need for a fourth dose of the COVID-19 vaccine - ForumDaily
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Pfizer announces need for fourth dose of COVID-19 vaccine

Pfizer CEO says the company is reporting to the Food and Drug Administration the need for a fourth dose of its COVID-19 vaccine, reports CBS.

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While the vaccine currently being produced by Pfizer with the help of BioNTech still protects against severe disease, the drug maker now believes another booster is needed to prevent infection.

“Right now, as we can see, a fourth booster is needed. The protection you get from the third is good enough, pretty good actually. But it takes another dose to not get infected,” Pfizer CEO Albert Burla said in an interview with Face the Nation that aired on March 13.

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Stephen Danehee, a spokesman for Pfizer, said Burla was referring to "early and preliminary" data, and pointed to a study released in January that looked at both the fourth dose of the currently approved formulation and another intended for the omicron variant. .

“We will continue to collect and evaluate all available data and maintain an open dialogue with regulators and public health authorities to help develop a COVID-19 vaccination strategy as the virus evolves,” Danehy said in a statement.

A White House spokesman sent requests to the FDA.

Burla previously described the company's research as "a significant package of data on the need for a fourth dose." His findings echoed trends seen by health authorities around the world that were looking into the effectiveness of the vaccine during the wave of omicron options earlier this year. Overall data released by the Centers for Disease Control and Prevention last month showed that the effectiveness of the vaccine against COVID-19 is high.

Emergency room visits dropped to 66% among those who received their third dose of one of the mRNA vaccines four to five months ago. The vaccine was 78% effective against COVID-19 among this group. Burla said that in addition to the fourth vaccine, the company is trying to create a new drug "that will protect against all variants, including omicron, for at least a year."

“Omicron was able to skillfully evade the immune protection we give. We also know that the duration of protection is not very long,” he said.

Federal health officials have previously said additional booster vaccinations will likely be needed to prevent new waves of the virus, although perhaps not until the fall for most people.

"We hope we can get enough time after our third vaccination to eventually have an annual COVID-19 booster," Dr. Peter Marks, the FDA's top vaccine official, said at the event in January.

The schedule was backed by executives from Moderna, which is also looking to trial new versions of its COVID-19 vaccine, hoping to get a green light from regulators ahead of a potential "fall booster season."

“The time has come to update the vaccine against the mutations that are currently circulating and increase resistance to these new variants. But we do run into a problem with these filings,” Moderna president Stephen Hoge told investors last month.

However, officials said the timing of the fourth dose could be accelerated for groups more vulnerable to the virus as it continues to spread. "I don't think you're going to hear any recommendations that are universal for everyone," Dr. Anthony Fauci, the president's chief medical adviser, told reporters last month.

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About half of all vaccinated adults and more than two-thirds of vaccinated older Americans received a booster dose, according to the CDC.

Although the rate of new cases and hospitalizations across the country continues to decline after the surge in omicrons earlier this year, more than a thousand COVID-19 deaths per day are still being recorded on average. In Europe, which also saw a sharp drop in infections following the omicron surge, the rate of new cases is picking up again after several countries lifted their pandemic restrictions.

“It is very likely that it will take into account which subset of people have reduced or no protection,” Fauci said.

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