Revolutionary discovery: scientists have found a cure for all types of cancer
The discovery of a team of scientists from Cardiff University may allow doctors to “tune” the human immune system against cancer cells. This may open the door to a universal cure for cancer. Writes about this with the BBC.
The method has not yet been clinically tested, but researchers say that it has great potential. Summary of work was published in the journal Nature Immunology.
The essence of the study was to search for "unusual" ways that the immune system fights cancerous tumors.
Scientists have discovered a special kind T lymphocyte - A cell that is responsible for the immune response in the human body.
However, the cell found by scientists, unlike others, can counteract different types of threats.
“There is a chance that this can cure all patients. Nobody used to think that this is possible, ”said Researcher Henry Sowell.
How it works
On the surface of T-lymphocytes (or T-cells) there are chemical receptors with which they determine antigens that are dangerous to the body.
A team of scientists managed to find a way to make them find the type of T-lymphocytes to attack a wide range of cancer cells.
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The method would be tested on cells of lung cancer, blood cancer, intestines, breast, bone, prostate, ovary and cervix.
The lymphocyte destroyed the cancer cells and did not touch the healthy ones.
How exactly a T-lymphocyte distinguishes cancer cells from healthy cells is not yet clear. Its receptor interacts with a molecule called MR1, which is on the surface of every cell in the human body.
It is believed that cancer cells "use" MR1 to mask the immune system. However, the T-lymphocyte found in Cardiff, the researchers believe, may receive a signal from MR1 that the cell metabolism is impaired and that it is a tumor cell.
“We are the first to describe a T cell detecting MR1 in cancer cells. Nobody has done this before, ”said researcher Harry Dalton.
This study is not the first in its field. Experiments on tuning the immune system against cancer have been around for quite some time.
The most famous of them is CAR-T. This anti-leukemia drug reprograms the immune system to counteract this type of cancer. In the case of CAR-T, T-lymphocytes are genetically reprogrammed to find and destroy cancer cells.
The modified lymphocytes are then returned to the patient’s body, where their number increases each time they collide with cancer cells.
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